I One Letter and Combination Chemotherapy Abbreviations

A: Dactinomycin

ABVD: Adriamycin/doxorubicin, bleomycin, vinblastine, dacarbazine AcFucy: Dactinomycin, 5-FU, cyclophosphamide AI: Aromatase inhibitor B: Bleomycin

BEP: Bleomycin, etoposide, cisplatin C: Cyclophosphamide

CDDP: cisplatin; cis-diamminedichloroplatinum

CHOPP-R: Cyclophosphamide, hydroxyurea, vincristine, procarbazine, prednisone, retuximab

CMFV: Cyclophosphamide, methotrexate, 5-FU, Vinblastine D: Doxorubicin E: Etoposide, VP-16 Epi: Epirubicin F: 5-FU

H: Hydroxyurea L: Chlorambucil

Lev: Levamisole

L-PAM: L-phenylalanine mustard M: Methotrexate

MAC: Methotrexate, dactinomycin, cyclophosphamide or chlorambucil MMC: Mitomycin

MOPP: Nitrogen mustard, vincristine, procarbazine, prednisone

O: Oncovin/vincristine P: Cisplatin Pr: Prednisolone T: Tamoxifen

TVPP: Thiotepa, vinblastine, procarbazine, prednisone V: Vinblastine

MVPP: Nitrogen mustard, vinblastine, procarbazine, prednisone

VAC: Vincristine, doxorubicin cyclophosphamide

VBM: Vinblastine, bleomycin, methotrexate

VBP: Vinblastine, bleomycin, cisplatin

VDC: Vincristine, doxorubicin, cyclophosphamide

II.  Chemotherapy Definitions

A.  Dose: Amount of chemotherapy administered

B.  Intensity: The amount of drug administered over time

C.  Schedule: Time interval for delivery of chemotherapy

D.  Chemotherapy cycle: One treatment of single or combination agents in the full course of therapy

E.  Chemotherapy course: Sequence of cycles for treatment

F.  Planning of treatment: Must take into consideration tumor type, extent of disease, patient’s comorbidities including renal function, age, social and emotional function, or if therapy is primary or salvage

III.  Delivery

Routes are IV, IM, PO, intraperitoneal (IP), or regional. Most chemotherapy is administered systemically, by IV. It can be given regionally to primary tumors or their metastasis. Intraperitoneal chemotherapy is administration of chemotherapy directly into the abdominopelvic cavity. Regional chemotherapy can be used to treat solitary organ lesions, such as liver metastasis. This occurs by obstruction of the outflow tract for a limited amount of time so that the chemotherapy can penetrate the tumor mass directly. It can also be directly administered to a cavity such as for pleural or pericardial lesions.

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